Personalized
medicine,
reinvented.
애티스랩은 3D 오가노이드 배양 기술을 기반으로 만성 질환 및 암 환자를 위한 맞춤형 치료와 약물 스크리닝 플랫폼을 개발하는 기업입니다.
Core Technology
오가노이드는 줄기세포로부터 자가 재생 및 자가 조직화를 통해 형성된 3차원 세포집합체로 오가노이드 배양 기술은 환자 맞춤형 재생 치료법의 핵심 기술입니다.
Applications
애티스랩은 오가노이드 기법을 활용하여 Cancer organ, Drug screening, Cell therapy 분야를 연구하고 있습니다.
Publications
애티스랩 연구진의 핵심 역량은
다양한 해외 유력 학술 논문들을 통해 입증되었습니다.
- Ju-Hyun An, Woo-Jin Song, Qiang Li, Dong-Ha Bhang, Hwa-Young Youn, (2021). 3D-culture models as drug-testing platforms in canine lymphoma and their cross talk with lymph node-derived stromal cells. J Vet Sci., 22(22), e25. https://doi.org/10.4142/jvs.2021.22.e25
- Seul Lee, Hyun-Soo Roh, Seong-Soo Song, Jimin Shin, Jangchoon Lee, Dong Ha Bhang, Byung Gak Kim, Sung Hee Um, Han-Sin Jeong, Kwan-Hyuck Baek, (2020). Loss of S6K1 But Not S6K2 in the Tumor Microenvironment Suppresses Tumor Growth by Attenuating Tumor Angiogenesis. Translational Oncology, 13(13), 100767. https://doi.org/10.1016/j.tranon.2020.100767
- Ju-Hyun An, Qiang Li, Min-Ok Ryu, A-Ryung Nam, Dong-Ha Bhang, Yun-Chan Jung, Woo-Jin Song, Hwa-Young Youn, (2020). TSG-6 in extracellular vesicles from canine mesenchymal stem/stromal is a major factor in relieving DSS-induced colitis. PLoS ONE, 15(15), e0220756. https://doi.org/10.1371/journal.pone.0220756
- Yong-Hee Kim, Myeong-Geun Oh, Dong Ha Bhang, Bang-Jin Kim, Sang-Eun Jung, Seok-Man Kim, Gottfried Dohr, Sun-Uk Kim, Sandra Ryeom , Buom-Yong Ryu, (2019). Testicular endothelial cells promote self-renewal of spermatogonial stem cells in rats. Biology Reproduction. Biology Reproduction, 101(101), 360-367. https://doi.org/10.1093/biolre/ioz105
- Dong Ha Bhang, Bang-Jin Kim, Byung Gak Kim, Keri Schadler, Kwan-Hyuck Baek, Yong Hee Kim, Wayland Hsiao, Bi-Sen Ding, Shahin Rafii, Mitchell J Weiss, Stella T Chou, Thomas F Kolon, Jill P Ginsberg, Buom-Yong Ryu, Sandra Ryeom, (2018). Testicular endothelial cells are a critical population in the germline stem cell niche. Nature Communication, 9(9), 4379. https://doi.org/10.1038/s41467-018-06881-z